Fat-to-glucose interconversion by hydrodynamic transfer of two glyoxylate cycle enzyme genes
نویسندگان
چکیده
منابع مشابه
Identification of genes involved in the glyoxylate regeneration cycle in Methylobacterium extorquens AM1, including two new genes, meaC and meaD.
The glyoxylate regeneration cycle (GRC) operates in serine cycle methylotrophs to effect the net conversion of acetyl coenzyme A to glyoxylate. Mutants have been generated in several genes involved in the GRC, and phenotypic analysis has been carried out to clarify their role in this cycle.
متن کاملEnzymes of the Glyoxylate Cycle in Germinating
of conversion of fat to carbohydrate in germinating castor beans. Of the four requisite enzymes, isocitritase (Equation 3) has been demonstrated by direct assay (l), while the presence of condensing enzyme (Equation 1), aconitase (Equation 2), and malate synthetase activity (Equation 4) has been inferred from isotope incorporation data. The rates of condensing enzyme and malate synthetase, as e...
متن کاملInhibitors of the Glyoxylate Cycle Enzyme ICL1 in Candida albicans for Potential Use as Antifungal Agents
Candida albicans is an opportunistic pathogen that causes candidiasis in humans. In recent years, metabolic pathways in C. albicans have been explored as potential antifungal targets to treat candidiasis. The glyoxylate cycle, which enables C. albicans to survive in nutrient-limited host niches and its. Key enzymes (e.g., isocitrate lyase (ICL1), are particularly attractive antifungal targets f...
متن کاملGlyoxylate cycle in toad urinary bladder: possible stimulation by aldosterone.
A homogenate of the toad urinary bladder epithelial cell layer has the two enzymatic activities unique to the glyoxylate cycle--isocitrate lyase (threo-Ds-isocitrate glyoxylate-lyase, EC 4.1.3.1) and malate synthase [L-malate glyoxylate-lyase (CA-acetylating), EC 4.1.3.2]--as well as the capacity to carry out CN-insensitive palmitoyl-CoA oxidation. When tissue is incubated in the presence of a ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Lipids in Health and Disease
سال: 2008
ISSN: 1476-511X
DOI: 10.1186/1476-511x-7-49